Native Methylation Meets Targeted Precision
Wasatch BioLabs' Direct Targeted Methylation Sequencing (dTMS) provides a scalable, cost-effective solution for region-specific analysis, ideal for applications where whole-genome sequencing is inefficient or expensive. Combining hybridization-based enrichment with nanopore sequencing, dTMS overcomes the limitations of traditional methods, including short-reads and synthetic DNA that erase native modifications.
dTMS enables the direct targeting of genes, regions, and epigenetic modifications, capturing complex sequences, and native methylation and hydroxymethylation with enhanced sensitivity and specificity.